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Home
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Duygu Tosun-Turgut, PhD
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Publications
Duygu Tosun-Turgut, PhD's Publications
Accelerated Cognitive Decline in Late Life Depression: The Role of Amyloid-β, Cortico-Limbic Volume, and White Matter Hyperintensities.
Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort.
APOE, ABCA7, and RASGEF1C are associated with earlier onset of amyloid deposition from more than 4000 harmonized positron emission tomography images.
Association of neighborhood disadvantage with Alzheimer's disease pathology and the stability of blood-based biomarker performance.
Characterizing amyloid and tau PET-based stages across the clinical continuum.
Comparison of plasma p-tau217/Aß42, p-tau217, and Aß42/Aß40 biomarkers by race to detect Alzheimer's disease.
Convergent large-scale network and local vulnerabilities underlie brain atrophy across Parkinson's disease stages: a worldwide ENIGMA study.
DRIPS: Domain Randomisation for Image-based Perivascular spaces Segmentation.
Genetic architecture of the limbic white matter microstructure in aging and Alzheimer's Disease.
Global network and local vulnerabilities underlie brain atrophy across Parkinson's disease stages.
Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer's Disease: Synthesis of Evidence from Observational and Interventional Trials.
Integrative effects of Telomere Length, Epigenetic Age, and Mitochondrial DNA abundance in Alzheimer's Disease.
Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals.
Neuroanatomical dimensions in major depression linked to cognition, adverse life events, self-harm, metabolomics and genetics.
Neuroimaging-based data-driven subtypes of spatiotemporal atrophy due to Parkinson's disease.
Radiomic and proteomic signatures of body mass index on brain ageing and Alzheimer's-like patterns of brain atrophy.
Response to "Brain Amyloid and Cognitive Decline in Late-Life Depression".
Revisiting Centiloids using AI.
Temporal sequence of amyloid and tau PET positivity: APOE -e4 and sex effects, and implications for Alzheimer's disease progression.
The effect of Alzheimer's disease genetic factors on limbic white matter microstructure.
Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks.
White Matter Abnormalities and Cognition in Aging and Alzheimer Disease.
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function.
A worldwide study of white matter microstructural alterations in people living with Parkinson's disease.
ADNI Biomarker Core: A review of progress since 2004 and future challenges.
Anxiety in late-life depression is associated with poorer performance across multiple cognitive domains.
Anxiety in late-life depression: Associations with brain volume, amyloid beta, white matter lesions, cognition, and functional ability.
Arterial spin labeling perfusion MRI in the Alzheimer's Disease Neuroimaging Initiative: Past, present, and future.
Association of CSF a-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study.
Association of CSF α-Synuclein Seed Amplification Assay Positivity with Disease Progression and Cognitive Decline: A Longitudinal Alzheimer's Disease Neuroimaging Initiative Study.
Automated Quality Evaluation Index for Arterial Spin Labeling Derived Cerebral Blood Flow Maps.
Brain aging patterns in a large and diverse cohort of 49,482 individuals.
Cortico-limbic volume abnormalities in late life depression are distinct from β amyloid and white matter pathologies.
Design and validation of the ADNI MR protocol.
Evolution of white matter hyperintensity segmentation methods and implementation over the past two decades; an incomplete shift towards deep learning.
Genetic and Clinical Correlates of AI-Based Brain Aging Patterns in Cognitively Unimpaired Individuals.
Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer's disease continuum.
Head-to-head comparison of leading blood tests for Alzheimer's disease pathology.
Head-to-head comparison of leading blood tests for Alzheimer's disease pathology.
Implementation and validation of face de-identification (de-facing) in ADNI4.
Individuals with Alzheimer's disease and low tau burden: Characteristics and implications.
MRI-free processing of tau PET images for early detection.
Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo.
Overview of ADNI MRI.
Overview of Alzheimer's Disease Neuroimaging Initiative and future clinical trials.
Personalizing progressive changes to brain structure in Alzheimer's disease using normative modeling.
Relationship between MRI brain-age heterogeneity, cognition, genetics and Alzheimer's disease neuropathology.
Self- and study partner-reported cognitive decline in older adults without dementia: The role of α-synuclein and amyloid biomarkers in the Alzheimer's Disease Neuroimaging Initiative.
Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
Sex, racial, and APOE-ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
Standardized statistical framework for comparison of biomarkers: Techniques from ADNI.
Timing of Alzheimer's disease biomarker progressions: A two-decade observational study from the Alzheimer's Disease Neuroimaging Initiative (ADNI).
Timing of changes in Alzheimer's disease plasma biomarkers as assessed by amyloid and tau PET clocks.
A universal neocortical mask for Centiloid quantification.
Accuracy of TrUE-Net in comparison to established white matter hyperintensity segmentation methods: An independent validation study.
AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale.
Efficacy assessment of an active tau immunotherapy in Alzheimer's disease patients with amyloid and tau pathology: a post hoc analysis of the "ADAMANT" randomised, placebo-controlled, double-blind, multi-centre, phase 2 clinical trial.
Five dominant dimensions of brain aging are identified via deep learning: associations with clinical, lifestyle, and genetic measures.
Genomic loci influence patterns of structural covariance in the human brain.
Hoarding Symptoms in Late Life Depression are Associated With Greater Executive Dysfunction and Disability and Poorer Response to Depression Treatment.
Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease.
Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group.
Personalising Alzheimer's Disease progression using brain atrophy markers.
Profiling and predicting distinct tau progression patterns: An unsupervised data-driven approach to flortaucipir positron emission tomography.
Relationship of Hoarding and Depression Symptoms in Older Adults.
Revealing Individual Neuroanatomical Heterogeneity in Alzheimer Disease Using Neuroanatomical Normative Modeling.
The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022.
A 1-year randomized controlled trial of a nutritional blend to improve nutritional biomarkers and prevent cognitive decline among community-dwelling older adults: The Nolan Study.
Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression.
Cognitive outcomes are differentially associated with depression severity trajectories during psychotherapy treatment for late life major depressive disorder.
Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4.
Multiple Cortical to Striatal Accumulation Trajectories of β-Amyloid: Do All Roads Lead to Rome?
Network-wise concordance of multimodal neuroimaging features across the Alzheimer's disease continuum.
Regional uptakes from early-frame amyloid PET and 18F-FDG PET scans are comparable independent of disease state.
Traumatic brain injury and post-traumatic stress disorder are not associated with Alzheimer's disease pathology measured with biomarkers.
β-amyloid PET harmonisation across longitudinal studies: Application to AIBL, ADNI and OASIS3.
ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer's disease.
Age-dependent brain morphometry in Major Depressive disorder.
Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum.
Deep learning for Alzheimer's disease: Mapping large-scale histological tau protein for neuroimaging biomarker validation.
Detection of β-amyloid positivity in Alzheimer's Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers.
Lower cerebral perfusion is associated with tau-PET in the entorhinal cortex across the Alzheimer's continuum.
Network-constrained technique to characterize pathology progression rate in Alzheimer's disease.
Thalamic Dorsomedial Nucleus Free Water Correlates with Cognitive Decline in Parkinson's Disease.
The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression.
The search for a convenient procedure to detect one of the earliest signs of Alzheimer's disease: A systematic review of the prediction of brain amyloid status.
Using imputation to provide harmonized longitudinal measures of cognition across AIBL and ADNI.
Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease.
White matter changes in drug-naïve Parkinson's disease patients with impulse control & probable REM sleep behavior disorders.
Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study.
Impact of hybrid supervision approaches on the performance of artificial intelligence for the classification of chest radiographs.
Improvements in Functional Disability After Psychotherapy for Depression Are Associated With Reduced Suicide Ideation Among Older Adults.
Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer's Disease Neuroimaging Initiative Depression Project.
Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults.
Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study.
Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases.
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
Chronic depressive symptomatology and CSF amyloid beta and tau levels in mild cognitive impairment.
Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort.
Preserved Structural Network Organization Mediates Pathology Spread in Alzheimer's Disease Spectrum Despite Loss of White Matter Tract Integrity.
Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults.
The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort.
Association between tau deposition and antecedent amyloid-β accumulation rates in normal and early symptomatic individuals.
Cortical Atrophy is Associated with Accelerated Cognitive Decline in Mild Cognitive Impairment with Subsyndromal Depression.
Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary Report.
Independent value added by diffusion MRI for prediction of cognitive function in older adults.
Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease.
Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology.
Amyloid status imputed from a multimodal classifier including structural MRI distinguishes progressors from nonprogressors in a mild Alzheimer's disease clinical trial cohort.
Cerebral amyloid is associated with greater white-matter hyperintensity accrual in cognitively normal older adults.
Diagnostic utility of ASL-MRI and FDG-PET in the behavioral variant of FTD and AD.
Progression of Regional Microstructural Degeneration in Parkinson's Disease: A Multicenter Diffusion Tensor Imaging Study.
Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease.
Brain amyloid-β burden is associated with disruption of intrinsic functional connectivity within the medial temporal lobe in cognitively normal elderly.
Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly.
Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia.
Cortical thickness and sulcal depth: insights on development and psychopathology in paediatric epilepsy.
Discriminative Power of Arterial Spin Labeling Magnetic Resonance Imaging and 18F-Fluorodeoxyglucose Positron Emission Tomography Changes for Amyloid-β-Positive Subjects in the Alzheimer's Disease Continuum.
Network Diffusion Model of Progression Predicts Longitudinal Patterns of Atrophy and Metabolism in Alzheimer's Disease.
Preliminary Evidence of Increased Hippocampal Myelin Content in Veterans with Posttraumatic Stress Disorder.
Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment.
Emerging β-amyloid pathology and accelerated cortical atrophy.
Multimodal MRI-based Imputation of the Aβ+ in Early Mild Cognitive Impairment.
Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.
CSF protein biomarkers predicting longitudinal reduction of CSF β-amyloid42 in cognitively healthy elders.
Effects of baseline CSF α-synuclein on regional brain atrophy rates in healthy elders, mild cognitive impairment and Alzheimer's disease.
Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults.
Locally linear embedding (LLE) for MRI based Alzheimer's disease classification.
Neuroimaging predictors of brain amyloidosis in mild cognitive impairment.
Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response.
The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment.
Voxel-wise co-analysis of macro- and microstructural brain alteration in mild cognitive impairment and Alzheimer's disease using anatomical and diffusion MRI.
Voxelwise multivariate analysis of multimodality magnetic resonance imaging.
Increased Cortical Thickness in Male-to-Female Transsexualism.
Patterns of Reduced Cortical Thickness in Late-Life Depression and Relationship to Psychotherapeutic Response.
Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: relationships to relapse and extended abstinence.
Deformation-based morphometry of prospective neurodevelopmental changes in new onset paediatric epilepsy.
Effects of childhood absence epilepsy on associations between regional cortical morphometry and aging and cognitive abilities.
Identifying cognitively healthy elderly individuals with subsequent memory decline by using automated MR temporoparietal volumes.
Impact of apolipoprotein E4-cerebrospinal fluid β-amyloid interaction on hippocampal volume loss over 1 year in mild cognitive impairment.
Impact of methodologic choice for automatic detection of different aspects of brain atrophy by using temporal lobe epilepsy as a model.
Intelligence and cortical thickness in children with complex partial seizures.
Joint assessment of structural, perfusion, and diffusion MRI in Alzheimer's disease and frontotemporal dementia.
MRI patterns of atrophy and hypoperfusion associations across brain regions in frontotemporal dementia.
Relationship between CSF biomarkers of Alzheimer's disease and rates of regional cortical thinning in ADNI data.
Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment.
Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects.
Joint analysis of structural and perfusion MRI for cognitive assessment and classification of Alzheimer's disease and normal aging.
Nonlinear time course of brain volume loss in cognitively normal and impaired elders.
Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study.
Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative.
An integrated multimodality MR brain imaging study: gray matter tissue loss mediates the association between cerebral hypoperfusion and Alzheimer's disease.
A geometry-driven optical flow warping for spatial normalization of cortical surfaces.
3-D analysis of cortical morphometry in differential diagnosis of Parkinson's plus syndromes: mapping frontal lobe cortical atrophy in progressive supranuclear palsy patients.
Cortical reconstruction using implicit surface evolution: accuracy and precision analysis.
Cortical surface alignment using geometry driven multispectral optical flow.
Program for Assisted Labeling of Sulcal Regions (PALS): description and reliability.
Cortical surface segmentation and mapping.
CRUISE: cortical reconstruction using implicit surface evolution.
Mapping techniques for aligning sulci across multiple brains.
