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Georgios Batsios, PhD
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Publications
Georgios Batsios, PhD's Publications
Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma.
Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in H3K27M-mutant gliomas.
The 1p/19q co-deletion induces targetable and imageable vulnerabilities in glucose metabolism in oligodendrogliomas.
Understanding and imaging PHGDH-driven intrinsic resistance to mutant IDH inhibition in gliomas.
GABA production induced by imipridones is a targetable and imageable metabolic alteration in diffuse midline gliomas.
Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.
Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-13C]-gluconolactone.
Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas.
A 13C/31P surface coil to visualize metabolism and energetics in the rodent brain at 3 Tesla.
Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.
Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer.
Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.
Acquisition and quantification pipeline for in vivo hyperpolarized 13 C MR spectroscopy.
Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone.
Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
Pan-cancer imaging of TERT expression using deuterium magnetic resonance spectroscopy-based assessment of pyruvate metabolism
Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment.
In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine.
MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.
In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma.
PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.
Hybrid multiband excitation multiecho acquisition for hyperpolarized (13) C spectroscopic imaging.
