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John Kurhanewicz, PhD
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Publications
John Kurhanewicz, PhD's Publications
Correction: Chen et al. Multivariate Framework of Metabolism in Advanced Prostate Cancer Using Whole Abdominal and Pelvic Hyperpolarized 13C MRI-A Correlative Study with Clinical Outcomes. Cancers 2025, 17, 2211.
Impact of Metastatic Microenvironment on Physiology and Metabolism of Small Cell Neuroendocrine Prostate Cancer Patient-Derived Xenografts.
Multivariate Framework of Metabolism in Advanced Prostate Cancer Using Whole Abdominal and Pelvic Hyperpolarized 13C MRI-A Correlative Study with Clinical Outcomes.
Translation of hyperpolarized [13C,15N2]urea MRI for novel human brain perfusion studies.
Distinguishing metabolic signals of liver tumors from surrounding liver cells using hyperpolarized 13 C MRI and gadoxetate.
Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations.
Protocol for producing hyperpolarized 13C-bicarbonate for clinical MRI of extracellular pH in aggressive tumors.
The impact of benign tissue within cancerous regions in the prostate: Characterizing sparse and dense prostate cancers on whole-mount histopathology and on multiparametric MRI.
Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials.
Clinically Translatable Hyperpolarized 13C Bicarbonate pH Imaging Method for Use in Prostate Cancer.
Co-Clinical Imaging Metadata Information (CIMI) for Cancer Research to Promote Open Science, Standardization, and Reproducibility in Preclinical Imaging.
Hyperpolarized [1-13 C] pyruvate MRSI to detect metabolic changes in liver in a methionine and choline-deficient diet rat model of fatty liver disease.
Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized 13C-Pyruvate MRI.
Parallel detection of chemical reactions in a microfluidic platform using hyperpolarized nuclear magnetic resonance.
Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [13 C,15 N2 ]urea + [1-13 C]pyruvate simultaneous perfusion and metabolic imaging.
Improving multiparametric MR-transrectal ultrasound guided fusion prostate biopsies with hyperpolarized 13 C pyruvate metabolic imaging: A technical development study.
Multiparametric Magnetic Resonance Imaging and Metabolic Characterization of Patient-Derived Xenograft Models of Clear Cell Renal Cell Carcinoma.
Clinical translation of hyperpolarized 13 C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging.
Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Immune Checkpoint Inhibitor Therapy in Prostate Cancer.
Identification of prostate cancer using multiparametric MR imaging characteristics of prostate tissues referenced to whole mount histopathology.
Magnetic resonance biomarkers in radiation oncology: The report of AAPM Task Group 294.
Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.
Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models.
Specialized computational methods for denoising, B1 correction, and kinetic modeling in hyperpolarized 13 C MR EPSI studies of liver tumors.
Tumor metabolism and neurocognition in CNS lymphoma.
Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures.
False positive PSMA PET for tumor remnants in the irradiated prostate and other interpretation pitfalls in a prospective multi-center trial.
Hyperpolarized 13 C MRI data acquisition and analysis in prostate and brain at University of California, San Francisco.
Simultaneous Metabolic and Perfusion Imaging Using Hyperpolarized 13C MRI Can Evaluate Early and Dose-Dependent Response to Radiation Therapy in a Prostate Cancer Mouse Model.
Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13 C MRSI.
Amino Acid-Derived Sensors for Specific Zn2+ Detection Using Hyperpolarized 13 C Magnetic Resonance Spectroscopy.
Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies.
First hyperpolarized [2-13C]pyruvate MR studies of human brain metabolism.
Hyperpolarized 13C MRI: State of the Art and Future Directions.
Hyperpolarized 13C-pyruvate MRI detects real-time metabolic flux in prostate cancer metastases to bone and liver: a clinical feasibility study.
Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer.
Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography.
NMR quantification of lactate production and efflux and glutamate fractional enrichment in living human prostate biopsies cultured with [1,6-13 C2 ]glucose.
Pulse sequence considerations for quantification of pyruvate-to-lactate conversion kPL in hyperpolarized 13 C imaging.
The Role of Lactate Metabolism in Prostate Cancer Progression and Metastases Revealed by Dual-Agent Hyperpolarized 13C MRSI.
Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging.
Zero-field nuclear magnetic resonance of chemically exchanging systems.
Assessing high-intensity focused ultrasound treatment of prostate cancer with hyperpolarized 13 C dual-agent imaging of metabolism and perfusion.
Detection of Bacteria-Specific Metabolism Using Hyperpolarized [2-13C]Pyruvate.
Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies.
Direct assessment of renal mitochondrial redox state using hyperpolarized 13 C-acetoacetate.
Dynamic diffusion-weighted hyperpolarized 13 C imaging based on a slice-selective double spin echo sequence for measurements of cellular transport.
Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology.
Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes.
In vivo hyperpolarization transfer in a clinical MRI scanner.
Investigation of analysis methods for hyperpolarized 13C-pyruvate metabolic MRI in prostate cancer patients.
Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI.
Measuring glucocorticoid receptor expression in vivo with PET.
Molecular detection of inflammation in cell models using hyperpolarized 13C-pyruvate.
Non-Invasive Assessment of Lactate Production and Compartmentalization in Renal Cell Carcinomas Using Hyperpolarized 13C Pyruvate MRI.
Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance in vivo.
Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma.
Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer.
Phase I study of dose escalation to dominant intraprostatic lesions using high-dose-rate brachytherapy.
Spatio-Temporally Constrained Reconstruction for Hyperpolarized Carbon-13 MRI Using Kinetic Models.
Technique development of 3D dynamic CS-EPSI for hyperpolarized 13 C pyruvate MR molecular imaging of human prostate cancer.
Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.
Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion.
Cancer recurrence monitoring using hyperpolarized [1-13C]pyruvate metabolic imaging in murine breast cancer model.
Characterization and stratification of prostate lesions based on comprehensive multiparametric MRI using detailed whole-mount histopathology as a reference standard.
Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques.
Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging.
Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Androgen Ablation Therapy in Prostate Cancer.
Hyperpolarized 13 C magnetic resonance evaluation of renal ischemia reperfusion injury in a murine model.
Impact of the integration of proton magnetic resonance imaging spectroscopy to PI-RADS 2 for prediction of high grade and high stage prostate cancer.
Improved multiparametric MRI discrimination between low-risk prostate cancer and benign tissues in a small cohort of 5α-reductase inhibitor treated individuals as compared with an untreated cohort.
Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma.
Sensitivity enhancement for detection of hyperpolarized 13 C MRI probes with 1 H spin coupling introduced by enzymatic transformation in vivo.
Unsaturation level decreased in bone marrow fat of postmenopausal women with low bone density using high resolution magic angle spinning (HRMAS) 1H NMR spectroscopy.
18F Fluorocholine Dynamic Time-of-Flight PET/MR Imaging in Patients with Newly Diagnosed Intermediate- to High-Risk Prostate Cancer: Initial Clinical-Pathologic Comparisons.
Combining hyperpolarized 13 C MRI with a liver-specific gadolinium contrast agent for selective assessment of hepatocyte metabolism.
Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13 C-lactate and 13 C-pyruvate in kidney and liver.
Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging.
Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry.
Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone.
Multiband spectral-spatial RF excitation for hyperpolarized [2-13 C]dihydroxyacetone 13 C-MR metabolism studies.
Non-invasive differentiation of benign renal tumors from clear cell renal cell carcinomas using clinically translatable hyperpolarized 13C pyruvate magnetic resonance.
Practical aspects of prostate MRI: hardware and software considerations, protocols, and patient preparation.
Separation of extra- and intracellular metabolites using hyperpolarized (13)C diffusion weighted MR.
Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses.
Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI.
Caged [(18)F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography.
Correlating high-resolution magic angle spinning NMR spectroscopy and gene analysis in osteoarthritic cartilage.
Dynamic UltraFast 2D EXchange SpectroscopY (UF-EXSY) of hyperpolarized substrates.
High-Resolution 3-T Endorectal Prostate MRI: A Multireader Study of Radiologist Preference and Perceived Interpretive Quality of 2D and 3D T2-Weighted Fast Spin-Echo MR Images.
Hyperpolarized [(13)C]ketobutyrate, a molecular analog of pyruvate with modified specificity for LDH isoforms.
Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor.
Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor.
A Domain Constrained Deformable (DoCD) Model for Co-registration of Pre- and Post-Radiated Prostate MRI.
Abnormal findings on multiparametric prostate magnetic resonance imaging predict subsequent biopsy upgrade in patients with low risk prostate cancer managed with active surveillance.
Hyperpolarized 13C MR for molecular imaging of prostate cancer.
Model-based feasibility assessment and evaluation of prostate hyperthermia with a commercial MR-guided endorectal HIFU ablation array.
Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance.
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized (13) C metabolites.
Reduced-FOV excitation decreases susceptibility artifact in diffusion-weighted MRI with endorectal coil for prostate cancer detection.
Role of endorectal MR imaging and MR spectroscopic imaging in defining treatable intraprostatic tumor foci in prostate cancer: quantitative analysis of imaging contour compared to whole-mount histopathology.
The changing role of imaging in clinical care.
Clinical utility of endorectal MRI-guided prostate biopsy: preliminary experience.
Cold spot mapping inferred from MRI at time of failure predicts biopsy-proven local failure after permanent seed brachytherapy in prostate cancer patients: implications for focal salvage brachytherapy.
Combined parallel and partial fourier MR reconstruction for accelerated 8-channel hyperpolarized carbon-13 in vivo magnetic resonance Spectroscopic imaging (MRSI).
Diffusion MR of hyperpolarized 13C molecules in solution.
Endorectal MRI and MR spectroscopic imaging of prostate cancer: developing selection criteria for MR-guided focal therapy.
High resolution (13)C MRI with hyperpolarized urea: in vivo T(2) mapping and (15)N labeling effects.
Hyperpolarized [1-13C]dehydroascorbate MR spectroscopy in a murine model of prostate cancer: comparison with 18F-FDG PET.
Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate.
Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor.
Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS.
Semiautomatic registration of digital histopathology images to in vivo MR images in molded and unmolded prostates.
Simultaneous multiagent hyperpolarized (13)C perfusion imaging.
The role of magnetic resonance imaging (MRI) in focal therapy for prostate cancer: recommendations from a consensus panel.
The role of metabolic imaging in radiation therapy of prostate cancer.
A method for simultaneous echo planar imaging of hyperpolarized ¹³C pyruvate and ¹³C lactate.
Does local recurrence of prostate cancer after radiation therapy occur at the site of primary tumor? Results of a longitudinal MRI and MRSI study.
Feasibility of MR imaging/MR spectroscopy-planned focal partial salvage permanent prostate implant (PPI) for localized recurrence after initial PPI for prostate cancer.
Frequency-specific SSFP for hyperpolarized ¹³C metabolic imaging at 14.1 T.
Generating contrast in hyperpolarized 13C MRI using ligand-receptor interactions.
Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas.
Imaging a functional tumorigenic biomarker in the transformed epithelium.
Local staging of prostate cancer: comparative accuracy of T2-weighted endorectal MR imaging and transrectal ultrasound.
Management of prostate cancer patients with lymph node involvement: a rapidly evolving paradigm.
Monitoring urea transport in rat kidney in vivo using hyperpolarized ¹³C magnetic resonance imaging.
Multi-kernel graph embedding for detection, Gleason grading of prostate cancer via MRI/MRS.
Multiparametric 3T endorectal mri after external beam radiation therapy for prostate cancer.
Perfusion and diffusion sensitive 13C stimulated-echo MRSI for metabolic imaging of cancer.
Progress in prostate cancer imaging.
Rapid sequential injections of hyperpolarized [1-¹³C]pyruvate in vivo using a sub-kelvin, multi-sample DNP polarizer.
Use of hyperpolarized [1-13C]pyruvate and [2-13C]pyruvate to probe the effects of the anticancer agent dichloroacetate on mitochondrial metabolism in vivo in the normal rat.
13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression.
A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent.
A pilot study of endorectal magnetic resonance imaging and magnetic resonance spectroscopic imaging changes with dutasteride in patients with low risk prostate cancer.
Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.
CADOnc©: An Integrated Toolkit For Evaluating Radiation Therapy Related Changes In The Prostate Using Multiparametric MRI.
Correlation of phospholipid metabolites with prostate cancer pathologic grade, proliferative status and surgical stage - impact of tissue environment.
Diagnostic tools and imaging methods in intervertebral disk degeneration.
Endorectal MRI after radiation therapy: questioning the sextant analysis.
Endorectal MRI of prostate cancer: incremental prognostic importance of gross locally advanced disease.
Generating super stimulated-echoes in MRI and their application to hyperpolarized C-13 diffusion metabolic imaging.
High-resolution magic angle spinning NMR spectroscopy of human osteoarthritic cartilage.
Human prostate cancer ZIP1/zinc/citrate genetic/metabolic relationship in the TRAMP prostate cancer animal model.
Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging.
Imaging of blood flow using hyperpolarized [(13)C]urea in preclinical cancer models.
In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine.
Interactive, multi-modality image registrations for combined MRI/MRSI-planned HDR prostate brachytherapy.
Magnetic resonance spectroscopic imaging of benign prostatic tissue: findings at 3.0 T compared to 1.5 T-initial experience.
Multimodal wavelet embedding representation for data combination (MaWERiC): integrating magnetic resonance imaging and spectroscopy for prostate cancer detection.
Prostate cancer: prediction of biochemical failure after external-beam radiation therapy--Kattan nomogram and endorectal MR imaging estimation of tumor volume.
Transatlantic Consensus Group on active surveillance and focal therapy for prostate cancer.
3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer.
A magnetic resonance spectroscopy driven initialization scheme for active shape model based prostate segmentation.
A novel application of 1H magnetic resonance spectroscopy: non-invasive identification of spermatogenesis in men with non-obstructive azoospermia.
Calculation of gestational age in late second and third trimesters by ex vivo magnetic resonance spectroscopy of amniotic fluid.
Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies.
Hyperpolarized (13)C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism.
Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors.
Investigation of tumor hyperpolarized [1-13C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI.
Locally recurrent prostate cancer after external beam radiation therapy: diagnostic performance of 1.5-T endorectal MR imaging and MR spectroscopic imaging for detection.
Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate.
Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo.
Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy.
Post-processing correction of the endorectal coil reception effects in MR spectroscopic imaging of the prostate.
Prostate cancer managed with active surveillance: role of anatomic MR imaging and MR spectroscopic imaging.
Prostate MRI and 3D MR spectroscopy: how we do it.
Semi supervised multi kernel (SeSMiK) graph embedding: identifying aggressive prostate cancer via magnetic resonance imaging and spectroscopy.
Semi-parametric time-domain quantification of HR-MAS data from prostate tissue.
Toward adaptive stereotactic robotic brachytherapy for prostate cancer: demonstration of an adaptive workflow incorporating inverse planning and an MR stealth robot.
Analysis of hyperpolarized dynamic 13C lactate imaging in a transgenic mouse model of prostate cancer.
Assessment of intervertebral disc degeneration with magnetic resonance single-voxel spectroscopy.
Evaluation of the ERETIC method as an improved quantitative reference for 1H HR-MAS spectroscopy of prostate tissue.
Generation of hyperpolarized substrates by secondary labeling with [1,1-13C] acetic anhydride.
Hyperpolarized [2-13C]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging.
Imaging considerations for in vivo 13C metabolic mapping using hyperpolarized 13C-pyruvate.
In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate.
Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice.
Metabolic, pathologic, and genetic analysis of prostate tissues: quantitative evaluation of histopathologic and mRNA integrity after HR-MAS spectroscopy.
Methods for metabolic evaluation of prostate cancer cells using proton and (13)C HR-MAS spectroscopy and [3-(13)C] pyruvate as a metabolic substrate.
Mucinous adenocarcinoma of the prostate: MRI and MR spectroscopy features.
Prostate cancer: sextant localization at MR imaging and MR spectroscopic imaging before prostatectomy--results of ACRIN prospective multi-institutional clinicopathologic study.
Quantitative metabolic profiles of 2nd and 3rd trimester human amniotic fluid using (1)H HR-MAS spectroscopy.
Spectral embedding based probabilistic boosting tree (ScEPTre): classifying high dimensional heterogeneous biomedical data.
T2-Weighted endorectal magnetic resonance imaging of prostate cancer after external beam radiation therapy.
(1)H HR-MAS spectroscopy for quantitative measurement of choline concentration in amniotic fluid as a marker of fetal lung maturity: inter- and intraobserver reproducibility study.
A clinical comparison of rigid and inflatable endorectal-coil probes for MRI and 3D MR spectroscopic imaging (MRSI) of the prostate.
Advances in MR spectroscopy of the prostate.
Class solution in inverse planned HDR prostate brachytherapy for dose escalation of DIL defined by combined MRI/MRSI.
Combined magnetic resonance imaging and magnetic resonance spectroscopy imaging in the diagnosis of prostate cancer: a systematic review and meta-analysis.
Compressed sensing for resolution enhancement of hyperpolarized 13C flyback 3D-MRSI.
Current and potential applications of clinical 13C MR spectroscopy.
DNP-Hyperpolarized C Magnetic Resonance Metabolic Imaging for Cancer Applications.
Dynamic contrast-enhanced MRI and MR diffusion imaging to distinguish between glandular and stromal prostatic tissues.
Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues.
Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies.
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
In vivo (1)H magnetic resonance spectroscopy of amniotic fluid and fetal lung at 1.5 T: technical challenges.
In vivo hyperpolarized 13C MR spectroscopic imaging with 1H decoupling.
Lactic acid and proteoglycans as metabolic markers for discogenic back pain.
Multiband excitation pulses for hyperpolarized 13C dynamic chemical-shift imaging.
Multiparametric magnetic resonance imaging in prostate cancer: present and future.
Pretreatment endorectal magnetic resonance imaging and magnetic resonance spectroscopic imaging features of prostate cancer as predictors of response to external beam radiotherapy.
Prostate cancer: is inapparent tumor at endorectal MR and MR spectroscopic imaging a favorable prognostic finding in patients who select active surveillance?
Prostate cancer: role of pretreatment MR in predicting outcome after external-beam radiation therapy--initial experience.
Pulse sequence for dynamic volumetric imaging of hyperpolarized metabolic products.
Quantification of choline- and ethanolamine-containing metabolites in human prostate tissues using 1H HR-MAS total correlation spectroscopy.
Role of magnetic resonance imaging and magnetic resonance spectroscopic imaging before and after radiotherapy for prostate cancer.
3D MR spectroscopic imaging in the evaluation of prostate cancer.
Diagnosis of prostate cancer in patients with an elevated prostate-specific antigen level: role of endorectal MRI and MR spectroscopic imaging.
Double spin-echo sequence for rapid spectroscopic imaging of hyperpolarized 13C.
High-speed 3T MR spectroscopic imaging of prostate with flyback echo-planar encoding.
Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T-initial experience.
In vivo 13 carbon metabolic imaging at 3T with hyperpolarized 13C-1-pyruvate.
Peripheral zone prostate cancer: accuracy of different interpretative approaches with MR and MR spectroscopic imaging.
Prostate cancer: sextant localization with MR imaging, MR spectroscopy, and 11C-choline PET/CT.
Validity of prostate-specific antigen as a tumour marker in men with prostate cancer managed by watchful-waiting: correlation with findings at serial endorectal magnetic resonance imaging and spectroscopic imaging.
Feasibility of magnetic resonance spectroscopy for evaluating fetal lung maturity.
High-grade prostatic intraepithelial neoplasia in patients with prostate cancer: MR and MR spectroscopic imaging features--initial experience.
High-resolution 3D MR spectroscopic imaging of the prostate at 3 T with the MLEV-PRESS sequence.
Magnetic resonance imaging and spectroscopy of prostate cancer.
Magnetic resonance spectroscopy in patients with locally confined prostate cancer: association of prostatic citrate and metabolic atrophy with time on hormone deprivation therapy, PSA level, and biopsy Gleason score.
Prostate cancer: endorectal MR imaging and MR spectroscopic imaging--distinction of true-positive results from chance-detected lesions.
Quantification of prostate MRSI data by model-based time domain fitting and frequency domain analysis.
Quantitative analysis of prostate metabolites using 1H HR-MAS spectroscopy.
Registration of MR prostate images with biomechanical modeling and nonlinear parameter estimation.
Three-dimensional conformal external beam radiotherapy compared with permanent prostate implantation in low-risk prostate cancer based on endorectal magnetic resonance spectroscopy imaging and prostate-specific antigen level.
Characterization of intervertebral disc degeneration by high-resolution magic angle spinning (HR-MAS) spectroscopy.
Correlation of HR-MAS spectroscopy derived metabolite concentrations with collagen and proteoglycan levels and Thompson grade in the degenerative disc.
Dynamic contrast-enhanced MRI in normal and abnormal prostate tissues as defined by biopsy, MRI, and 3D MRSI.
Expandable and rigid endorectal coils for prostate MRI: impact on prostate distortion and rigid image registration.
Improved signal to noise in high-resolution magic angle spinning total correlation spectroscopy studies of prostate tissues using rotor-synchronized adiabatic pulses.
Prostatic biopsy directed with endorectal MR spectroscopic imaging findings in patients with elevated prostate specific antigen levels and prior negative biopsy findings: early experience.
Sequence design for magnetic resonance spectroscopic imaging of prostate cancer at 3 T.
Endorectal MR imaging and MR spectroscopic imaging for locally recurrent prostate cancer after external beam radiation therapy: preliminary experience.
Image registration for prostate MR spectroscopy using modeling and optimization of force and stiffness parameters.
Inverse planning for HDR prostate brachytherapy used to boost dominant intraprostatic lesions defined by magnetic resonance spectroscopy imaging.
Organ-confined prostate cancer: effect of prior transrectal biopsy on endorectal MRI and MR spectroscopic imaging.
Preliminary assessment of magnetic resonance spectroscopic imaging in predicting treatment outcome in patients with prostate cancer at high risk for relapse.
Prostate cancer localization with endorectal MR imaging and MR spectroscopic imaging: effect of clinical data on reader accuracy.
Prostate depiction at endorectal MR spectroscopic imaging: investigation of a standardized evaluation system.
Time to metabolic atrophy after permanent prostate seed implantation based on magnetic resonance spectroscopic imaging.
Use of MRI and spectroscopy in evaluation of external beam radiotherapy for prostate cancer.
Activation of pro-gelatinase B by endometase/matrilysin-2 promotes invasion of human prostate cancer cells.
Magnetic resonance imaging and spectroscopic imaging of prostate cancer.
Proton HR-MAS spectroscopy and quantitative pathologic analysis of MRI/3D-MRSI-targeted postsurgical prostate tissues.
Combined magnetic resonance imaging and spectroscopic imaging approach to molecular imaging of prostate cancer.
Prostate cancer tumor volume: measurement with endorectal MR and MR spectroscopic imaging.
Brachytherapy for prostate cancer: endorectal MR imaging of local treatment-related changes.
Dualband spectral-spatial RF pulses for prostate MR spectroscopic imaging.
Localized prostate cancer: effect of hormone deprivation therapy measured by using combined three-dimensional 1H MR spectroscopy and MR imaging: clinicopathologic case-controlled study.
Magnetic resonance imaging and spectroscopic imaging of prostate cancer.
Magnetic resonance imaging and spectroscopic imaging: Improved patient selection and potential for metabolic intermediate endpoints in prostate cancer chemoprevention trials.
Single-voxel oversampled J-resolved spectroscopy of in vivo human prostate tissue.
Spectroscopy in prostate cancer: hope or hype?
Time-dependent effects of hormone-deprivation therapy on prostate metabolism as detected by combined magnetic resonance imaging and 3D magnetic resonance spectroscopic imaging.
Clinical application of BASING and spectral/spatial water and lipid suppression pulses for prostate cancer staging and localization by in vivo 3D 1H magnetic resonance spectroscopic imaging.
Sextant localization of prostate cancer: comparison of sextant biopsy, magnetic resonance imaging and magnetic resonance spectroscopic imaging with step section histology.
The prostate: MR imaging and spectroscopy. Present and future.
Three-dimensional magnetic resonance spectroscopic imaging of brain and prostate cancer.
Very selective suppression pulses for clinical MRSI studies of brain and prostate cancer.
Prostate cancer: localization with three-dimensional proton MR spectroscopic imaging--clinicopathologic study.
Prostate cancer: prediction of extracapsular extension with endorectal MR imaging and three-dimensional proton MR spectroscopic imaging.
Static field intensity modulation to treat a dominant intra-prostatic lesion to 90 Gy compared to seven field 3-dimensional radiotherapy.
Detection of recurrent prostate cancer after cryosurgery.
In vivo lactate editing with simultaneous detection of choline, creatine, NAA, and lipid singlets at 1.5 T using PRESS excitation with applications to the study of brain and head and neck tumors.
Localizing prostate cancer in the presence of postbiopsy changes on MR images: role of proton MR spectroscopic imaging.
High spatial resolution and speed in MRSI.
Improved solvent suppression and increased spatial excitation bandwidths for three-dimensional PRESS CSI using phase-compensating spectral/spatial spin-echo pulses.
Improved water and lipid suppression for 3D PRESS CSI using RF band selective inversion with gradient dephasing (BASING).
Detection of locally recurrent prostate cancer after cryosurgery: evaluation by transrectal ultrasound, magnetic resonance imaging, and three-dimensional proton magnetic resonance spectroscopy.
Hormonal ablation of prostatic cancer: effects on prostate morphology, tumor detection, and staging by endorectal coil MR imaging.
Prostate cancer: metabolic response to cryosurgery as detected with 3D H-1 MR spectroscopic imaging.
Prostate carcinoma: MR imaging findings after cryosurgery.
Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.7-cm3) spatial resolution.
Citrate as an in vivo marker to discriminate prostate cancer from benign prostatic hyperplasia and normal prostate peripheral zone: detection via localized proton spectroscopy.
Prostate cancer: effect of postbiopsy hemorrhage on interpretation of MR images.
13-cis-retinoic acid-mediated growth inhibition of DU-145 human prostate cancer cells.
31P magnetic resonance spectroscopy after combined hyperthermia and radiation.
Carcinoma of the prostate gland: MR imaging with pelvic phased-array coils versus integrated endorectal--pelvic phased-array coils.
Citrate alterations in primary and metastatic human prostatic adenocarcinomas: 1H magnetic resonance spectroscopy and biochemical study.
Effect of glucose and confluency on phosphorus metabolites of perfused human prostatic adenocarcinoma cells as determined by 31P MRS.
Magnetic resonance spectroscopy in prostate disease: diagnostic possibilities and future developments.
Phosphorus metabolite characterization of human prostatic adenocarcinoma in a nude mouse model by 31P magnetic resonance spectroscopy and high pressure liquid chromatography.
31P magnetic resonance spectroscopy (MRS) of experimental orbital myositis.
31P spectroscopy of the human prostate gland in vivo using a transrectal probe.
Characterization of prostate cancer, benign prostatic hyperplasia and normal prostates using transrectal 31phosphorus magnetic resonance spectroscopy: a preliminary report.
31P magnetic resonance spectroscopy of animal uveal melanoma.
Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats.
MRS of ischemic/hypoxic brain disease.