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Luke Bonham, MD
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Publications
Luke Bonham, MD's Publications
Aging activates escape of the silent X chromosome in the female mouse hippocampus.
DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Integrative effects of Telomere Length, Epigenetic Age, and Mitochondrial DNA abundance in Alzheimer's Disease.
Reduced levels of angiogenesis biomarkers predict increased symptom severity in Chinese Americans with Alzheimer's disease with demographic-specific effect.
C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes.
The role of interferon signaling in neurodegeneration and neuropsychiatric disorders.
Association of Optic Nerve Head and Macular Optical Coherence Tomography Measures With Glaucoma-Related Disability.
C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
Early-onset Alzheimer's disease explained by polygenic risk of late-onset disease?
FTLD targets brain regions expressing recently evolved genes.
Genetic overlap between cortical brain morphometry and frontotemporal dementia risk.
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.
Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy.
Case Report: Novel CSF1R Variant in a Patient With Behavioral Variant Frontotemporal Dementia Syndrome With Prodromal Repetitive Scratching Behavior.
Dissecting the clinical heterogeneity of early-onset Alzheimer's disease.
Radiogenomics of C9orf72 Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment.
The Role of Microglia in Inherited White-Matter Disorders and Connections to Frontotemporal Dementia.
A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease.
Diagnostic and interventional magnetic resonance neurography diagnosis of brachytherapy seed-mediated pudendal nerve injury: a case report.
Needle Heating During Interventional Magnetic Resonance Imaging at 1.5- and 3.0-T Field Strengths.
Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases.
Alzheimer Disease-associated Cortical Atrophy Does not Differ Between Chinese and Whites.
Evidence-Based Criteria for Determining Peripapillary OCT Reliability.
Exploring Patient Motivations and Impact of Asian Blepharoplasty.
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia.
Immunological signatures in frontotemporal lobar degeneration.
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
Recent advances in the genetics of frontotemporal dementia.
The Radiogenomics of Late-onset Alzheimer Disease.
The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease.
Comparative Analysis of Body Radiologist to Neuroradiologist Evaluation of the Spine in Trauma Settings.
Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
CXCR4 involvement in neurodegenerative diseases.
Frequency of frontotemporal dementia gene variants in C9ORF72, MAPT, and GRN in academic versus commercial laboratory cohorts.
Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer's Disease.
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer's Disease Pathology and Shows Differential Expression in Transgenic Mice.
MR Imaging-Guided Cryoneurolysis of the Sural Nerve.
Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes.
Protein network analysis reveals selectively vulnerable regions and biological processes in FTD.
Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.
Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex.
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease.
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia.
Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging.
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.
Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression.
The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer's disease.
APOE Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals.
Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.
Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer's disease.
The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia.
Variation in longevity gene KLOTHO is associated with greater cortical volumes.
