Suresh Udutha, PhD Postdoctoral Scholar suresh.udutha@ucsf.edu UCSF Profile Research Lab Cancer Metabolic Imaging & Therapy Lab | Viswanath Lab Publications Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma. Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in H3K27M-mutant gliomas. The 1p/19q co-deletion induces targetable and imageable vulnerabilities in glucose metabolism in oligodendrogliomas. GABA production induced by imipridones is a targetable and imageable metabolic alteration in diffuse midline gliomas. Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas. Identification and characterization of stress degradation products of sumatriptan succinate by using LC/Q-TOF-ESI-MS/MS and NMR: Toxicity evaluation of degradation products. See All Publications
