This project aims to identify important immunologic pathways – both in the bloodstream and in fat tissue – that predict Type 2 diabetes mellitus (T2DM) specifically in the context of treated HIV infection in order to help identify new preventive and therapeutic targets. The Noworolski laboratory is focused on providing existing and novel noninvasive measures of fat and fibrosis to help elucidate their roles in predicting T2DM in this population.