Image
Developing Novel Clinical Applications for ESI

In addition to existing clinical research projects in brain tumor and epilepsy patients, we are also in the process of developing several protocols and procedures for examining novel clinical populations. Ongoing projects including conducting ESI studies on patients with Schizophrenia, Mild Cognitive Impairments, Parkinson's disease, Autism, Traumatic Brain Injury, Stroke, Focal-Hand Dystonia and Agenesis of the Corpus-Collosum.

Center versus peripheral vowel productions in a sample subject.
A, Acoustic variation
across repeated productions, shown in 2D formant frequency space. Green represents center productions; red represents peripheral productions; black represents remaining productions.
B, A source localization algorithm (Owen et al., 2012) determined the coordinates and field strength of the M100 peak (MNI56,24, 8 in this subject).
C, MEG traces aligned tovowel onset, separated into center and peripheral trials as determined by A. Shaded regions
represent SE (n100); vertical bars on the y-axis represent SIS magnitude.